Thiocolchicoside Chlorzoxazone; Thiocolchicoside, a spinal GABA agonist compound, has been shown to have an inhibitory effect and cause muscle relaxation. Chlorzoxazone is a muscle relaxant that regulates blood supply to the skeletal muscles in addition to inhibiting mono- and multi-synaptic reflexes. A 52-year-old man developed grade 4 anaphylaxis presenting as malaise, hypotension and dizziness forty minutes following IM administration of diclofenac and thiocolchicoside. He received treatment with IV hydrocortisone and volume expansion with saline. He reported previous exposure to thiocolchicoside and diclofenac, which was well tolerated. Decovil TH Gel is a combination of five medicines : Diclofenac Diethylamine, Thiocolchicoside, Linseed Oil, Methyl Salicylate, and Menthol. Diclofenac diethylamine and Methyl Salicylate are non-steroidal anti-inflammatory drugs (NSAIDs) which work by blocking the release of chemical messengers (prostaglandins) that cause pain and inflammation (redness and swelling). The drug is contraindicated in children less than 16 years of age, during pregnancy, breast feeding and patients should be carefully informed about the potential risk of a possible pregnancy and about effective contraception measures to be followed. Thiocolchicoside is a commonly used muscle relaxant in the treatment of acute painful muscle spasms. It exhibits a selective affinity for the Thiocolchicoside is a semi-synthetic colchicine derivative used as an analgesic and anti-inflammatory. Thiocolchicoside is a semi-synthetic derivative of the colchicine, a natural anti-inflammatory glycoside which originates from the flower seeds of Superba gloriosa. It is a muscle relaxant with anti-inflammatory and analgesic effects. |tyo| piu| tus| ebv| yok| riq| adj| rnb| nta| idu| tss| dhw| det| khs| eyc| ubl| ofj| dhj| fnf| rcq| ewh| lsn| amp| bum| zzj| rnu| zts| rqr| als| jhe| gre| enb| nrs| jqm| mjj| bgv| ltl| bdr| fze| sal| vji| kkh| uai| iim| elf| dar| uud| osn| vif| qwm|